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July 14, 2018

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Poker’s world championship will play down to a final table tonight at theRio

Justin M. Bowen

Joe Cada, 21, wraps his arms around his $8.5 million winnings after beating Darvin Moon in the final round of the 2009 World Series of Poker at theRio.

By Case Keefer ( contact )

Published Wednesday, July 11, 2018 | 2:10 a.m.

Updated Wednesday, July 11, 2018 | 12:04 p.m.

Launch slideshow »

Of all the World Series of Poker Main Event champions in the last 15 years since the tournament exploded in popularity, Joe Cada has proven to be one of the most successful.

The Shelby Township, Mich., native never slowed down after becoming poker’s world champion in the 2009 Main Event. He’s gone on to win two more WSOP championship bracelets, including one earlier this summer, and pushed his career tournament earnings to more than $10 million.

Cada has a chance to further separate himself and pull off one of the greatest feats in World Series of Poker history today at the Rio. The 30 year old was one of 26 players remaining out of a starting field of 7,874 in this year’s $10,000 buy-in Main Event when play wrapped up at around 1 a.m. this morning.

The tournament will resume at noon on Wednesday and continue until a final table of nine players emerges. PokerGo will stream the action until 6:30 p.m., when ESPN2 picks up coverage and airs the rest.

Cada is looking to become the first former champion to return to the final table since 2004, when 1995 winner Dan Harrington finished fourth. A final-table appearance comes with a guaranteed payout of $1 million, while the eventual winner will make $8.8 million — $300,000 more than Cada’s prize nine years ago.

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Sylvain Loosli, 26, a poker professional originally from Toulon, France, but now residing in London, during the final table of the World Series of Poker $10,000 buy-in no-limit Texas Hold 'Em tournament at the Rio Monday, Nov. 4, 2013.

Cada will by no means have an easy route to the final table. He currently sits 19th in chips with 8.85 million, and blind levels are at a costly 1 million-2 million with a 300,000 ante.

And although he’s the most famous survivor through nearly 64 hours of play, he’s far from the only notable. Four other bracelet winners are still in the field — Yueqi Zhu, Eric Froehlich, Ivan Luca and Barry Hutter — along with another player who’s also made a Main Event final table in Sylvian Loosli, who finished fourth in 2013.

Nasopharyngeal colonization precedes invasive disease and may exceed 50% in some populations (for a review, see reference 13 ). Since this organism is a strict human pathogen, this asymptomatic carriage likely represents the primary reservoir leading to horizontal spread. Therefore, factors influencing rates and density of bacterial colonization will affect transmission and incidence of infection in the population. Currently, specific host-pathogen interactions that affect H. influenzae colonization are incompletely characterized due to the lack of a convenient and genetically tractable animal model system.

Host genetic differences likely play a significant role in conferring predisposition to both colonization and infection. For example, initial colonization of artificial animal model systems could be limited by multiple factors, including the lack of an essential receptor(s), the availability of nutrients, the indigenous flora, and the innate and/or adaptive immune responses. Previous studies in our laboratory have described colonization dynamics of H. influenzae in the murine nasopharynx ( 29 , 46 ), suggesting that an essential receptor or nutrient acquisition is not lacking in this artificial host. In particular, H. influenzae colonization of C57BL/6 mice is associated with recruitment of an inflammatory infiltrate comprised primarily of neutrophils to the nasal spaces, resulting in bacterial clearance mediated by multiple components of innate immunity ( 46 ). However, continued studies revealed that BALB/c mice are more susceptible to both Hib and NTHI colonization, suggesting that these innate immune factors are less effective in mice of this background.

Differing degrees of susceptibility to infection by inbred mouse strains have been characterized for numerous human bacterial pathogens including Streptococcus pneumoniae ( Mirco Gaspari black paint splattered denim jacket Cheap Sale Best Prices EpyhG4JdH
), Streptococcus pyogenes ( 34 ), Staphylococcus aureus ( 43 ), Mycobacterium tuberculosis ( 35 , 38 ), and Salmonella enterica ( 4 ). Specifically, C57BL/6 and BALB/c mice have been shown to generate distinct immune responses against Helicobacter pylori ( Iro Maloma denim jacket Low Shipping Cheap Price Looking For Free Shipping Enjoy Factory Outlet Sale Online Sale For Nice F6c6fuqJ
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), and BALB/c mice are more susceptible to S. pneumoniae and H. influenzae infection in a model of otitis media ( Discount Store Thom Browne Eyewear round shaped glasses Discounts Online p6QCR
). As we have previously described innate immunity-mediated clearance of H. influenzae by C57BL/6 mice and observed an increased susceptibility of BALB/c mice to various H. influenzae strains, we set forth to identify host factors that impact colonization in the BALB/c mouse background. Unlike what is observed in the C57BL/6 background, colonization of BALB/c mice was limited by adaptive immune components. Moreover, natural immunoglobulin G (IgG) antibody from conventionally reared BALB/c mice that bound to the bacterial surface was present at the nasopharyngeal mucosa, and serum Ig exhibited bactericidal activity against these genetically diverse H. influenzae strains. Our analysis of host factors affecting colonization of BALB/c mice suggests that conserved targets of IgG-mediated mucosal immunity may exist for this species.

Lauren Sylwanowicz, MD and Andrew Wong, MD, MBA

University of California, Irvine, Department of Emergency Medicine, Orange, CA

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Visual EM

History of present illness:

A 31-year-old male presented to the emergency department (ED) with worsening constant left sided throat pain over the past four months. The patient reports that he was brushing his teeth when his dog jumped onto his back causing his toothbrush to puncture the back of his throat, resulting in immediate bleeding and discomfort. The bleeding subsided and the patient did not seek medical care. The pain radiated to his left ear and the back of the neck. He also noted a change in his voice. The day before presenting to the ED the patient noted subjective fevers, hemoptysis and drooling, which led him to seek medical care.

Significant findings:

The photograph demonstrates an area of ulcerative tissue at the left palatine tonsil without surrounding erythema or purulent drainage. The computed tomography (CT) scan shows a large ulceration of the left soft palate and palatine tonsil (red arrow). There is no evidence of skull base osteomyelitis. There is suppurative lymphadenopathy with partial left jugular vein compression due to mass effect (yellow highlight). There is mild nasopharyngeal airway narrowing with architectural distortion (blue arrow), but no other evidence of airway obstruction.

Discussion:

The oral cavity is prone to trauma leading to the formation of superficial ulcerations. There are many causes of mechanical trauma, most commonly accidental biting. Chemical, electrical and thermal insults are also possibilities. Poor fitting dental devices and fractured or malformed teeth can also be etiologies. 1 Traumatic ulcerations are most common in children given bruxism and thumb sucking. However, a broad differential must be considered including malignant and premalignant lesions, infections of the oral mucosa, aphthous ulcerations and autoimmune diseases. 2, 3

Chronic ulcerations are associated with superimposed infection, but there has not been established an association of malignant transformation of the oral mucosa after trauma. If there is an unclear history at presentation, the provider must consider referral for a biopsy to exclude malignancy. Most ulcerations from mechanical or thermal trauma resolve in ten to fourteen days. Antibiotics can be considered to prevent secondary infection if the ulceration is severe; however, most resolve without antibiotics. Supportive measures to consider include removal of irritant, mouth guards, soft diet, sodium chloride mouth rinse, topical corticosteroids or anesthetics. Triamcinolone acetonide and fluocinonide gel are recommended for analgesia. 2

Bipolar Depression Unscripted is a trademark of Sunovion Pharmaceuticals Inc. All other trademarks and registered trademarks are the property of their respective owners. Sunovion Pharmaceuticals Inc. is a U.S. subsidiary of Sumitomo Dainippon Pharma Co., Ltd. SUNOVION and are registered trademarks of Sumitomo Dainippon Pharma Co., Ltd. ©2017 Sunovion Pharmaceuticals Inc. All rights reserved. 04/17 LAT439-17